You might have your biopsy under local or general anaesthetic. If you have it under general anaesthetic, you will be asleep during the whole procedure. This means that you won’t feel or hear anything. You might feel a bit drowsy or confused when you wake up.
If you have it under local anaesthetic, the doctor injects an anaesthetic into the perineum. This numbs the area.
They put an ultrasound probe into your back passage to show the prostate gland. They use the ultrasound to guide a biopsy needle through the perineum and into the prostate. Doctors may also use the results of your MRI scan to help them work out where to take the biopsies from. They then take a small number of samples.
Sometimes doctors may decide to take between 30 to 50 samples. This is called a transperineal template biopsy. They use a template (or grid) with lots of holes over your perineum and guide the needle through the template.